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Zambada García's organization, the Sinaloa Cartel, receives multi-ton quantities of cocaine, mostly by sea from Colombian sources. He may have had plastic surgery and disguised himself to move throughout Mexico. Zambada is likely Mexico's most enduring and powerful drug lord.
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Zambada has now possibly assumed full command of the Sinaloa Cartel.
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Zambada headed the Sinaloa Cartel in partnership with Joaquín "El Chapo" Guzmán, until 2016 when El Chapo was captured. Zambada has been wanted by Mexico's attorney general's office since 1998, when it issued bounties totaling $2.8 million USD on him and five other leaders of the Juárez Cartel. Zambada has historically worked closely with the Juárez Cartel and the Carrillo Fuentes family, while maintaining independent ties to Colombian cocaine suppliers. Taking advantage of the pressure being placed on the Tijuana Cartel, other drug bosses, most notably Ismael Zambada and Joaquín Guzmán, began to encroach on strongholds in northwestern Mexico, leading to full-scale war. The Arellano Felix Organization (Tijuana Cartel), the largest and most sophisticated of the Mexican cartels at the time, received the brunt of the blows. In 2006, the administration of President Felipe Calderon launched an offensive against Mexico's drug trafficking networks. The Sinaloa Cartel drug lords were active in the states of Sinaloa, Durango, Chihuahua, Sonora, Nuevo León, and Michoacán.
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The former farmer turned drug lord began his criminal career by smuggling as little as a few kilograms of drugs at a time however, it was only to gain a foothold before he went about increasing his gang's production of heroin and marijuana while also solidifying his position as a trafficker of Félix Gallardo was arrested in 1989, his organization split into two opposing factions: the Tijuana Cartel whose leadership was inherited by his nephews and heirs, the Arellano Félix brothers and the Sinaloa Cartel whose leadership fell to former lieutenants Héctor Luis Palma Salazar, Adrián Gómez González, Ismael Zambada García, Ignacio Coronel Villarreal, and Joaquín Guzmán Loera ( El Chapo).
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